Zachodniopomorski Uniwersytet Technologiczny w Szczecinie

Wydział Biotechnologii i Hodowli Zwierząt - Biotechnology (S2)
specjalność: Biotechnology in Animal Production and Environmental Protection

Sylabus przedmiotu Molecular Modelling of Enzymes:

Informacje podstawowe

Kierunek studiów Biotechnology
Forma studiów studia stacjonarne Poziom drugiego stopnia
Tytuł zawodowy absolwenta magister inżynier
Obszary studiów charakterystyki PRK, kompetencje inżynierskie PRK
Profil ogólnoakademicki
Moduł
Przedmiot Molecular Modelling of Enzymes
Specjalność Biotechnology in Animal Production and Environmental Protection
Jednostka prowadząca Katedra Mikrobiologii i Biotechnologii
Nauczyciel odpowiedzialny Radosław Drozd <Radoslaw.Drozd@zut.edu.pl>
Inni nauczyciele
ECTS (planowane) 2,0 ECTS (formy) 2,0
Forma zaliczenia zaliczenie Język angielski
Blok obieralny 7 Grupa obieralna 2

Formy dydaktyczne

Forma dydaktycznaKODSemestrGodzinyECTSWagaZaliczenie
laboratoriaL3 15 1,00,41zaliczenie
wykładyW3 15 1,00,59zaliczenie

Wymagania wstępne

KODWymaganie wstępne
W-1The elementary knowledge of genetics, molecular genetics, cell biology and evolution.
W-2The intermadiate levele of knowledge of organic and inorganic chemistry, biochemistry, biophysics, English at intermediate level

Cele przedmiotu

KODCel modułu/przedmiotu
C-1Developing skills of selection of appropriate bioinformatics tools to solve and analyze the structure of proteins
C-2Mastering the ability to combine and correct interpretation of information relating to various levels of organization of protein structures

Treści programowe z podziałem na formy zajęć

KODTreść programowaGodziny
laboratoria
T-L-1The introduction to proteins molecular structure part I2
T-L-2The introduction to proteins molecular structure part II2
T-L-3The in silico methods of proteins structure II and III level determination4
T-L-4Methods of enzymes structure ligand binding site determination.2
T-L-5The methods for the effective ligands design for the enzymes activity modulation.5
15
wykłady
T-W-1Principles of proteins structure organisation part I. Methods for the data mining for protein structure on their I level.2
T-W-2Priciples of proteins structure organisation part II. Methods for the data mining for protein structure on their II and III level.2
T-W-3Computionial methods for prediction of localisation the enzymes acitive site.2
T-W-4Computational methods for enzymes catalytic sites properities determination.2
T-W-5Modeling of the catalytic properities of enzymes - pH and thermal optima,2
T-W-6Molecular docking as tool for design an enzymes inhibitors. Part I2
T-W-7Molecular docking as tool for design an enzymes inhibitors. Part II2
T-W-8Molecular modeling software for enzyme analysis and modelling1
15

Obciążenie pracą studenta - formy aktywności

KODForma aktywnościGodziny
laboratoria
A-L-1Participation in the classes.15
A-L-2Individual study of training materials8
A-L-3consultations2
25
wykłady
A-W-1Participation in lectures.15
A-W-2Consultation2
A-W-3Preparation for passing the lecture content.8
25

Metody nauczania / narzędzia dydaktyczne

KODMetoda nauczania / narzędzie dydaktyczne
M-1Information lectures
M-2Explanation or clarification
M-3Description

Sposoby oceny

KODSposób oceny
S-1Ocena podsumowująca: multimedial presentation
S-2Ocena formująca: multimedia presentation

Zamierzone efekty uczenia się - wiedza

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
BTap_2A_BTA-S-O7.2_W01
Student has knowledge about the organization and structural relationships of proteins. He knows bioinformatic methods and tools for the analysis of protein structures. Has knowledge about the possibilities and consequences of manipulation in protein structures.
BTap_2A_W01C-1, C-2T-L-1, T-L-3, T-L-5M-1, M-2, M-3S-2

Zamierzone efekty uczenia się - umiejętności

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
BTap_2A_BTA-S-O7.2_U01
Correctly applying a bioinformatic tools to 3D enzymes structure solving
BTap_2A_U05C-1, C-2T-W-1, T-W-2, T-W-3, T-W-4M-3S-2

Zamierzone efekty uczenia się - inne kompetencje społeczne i personalne

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
BTap_2A_BTA-S-O7.2_K01
Understands the consequences of modifying protein structures on the functioning of living organisms
BTap_2A_K02C-1, C-2T-L-1, T-L-3, T-L-5M-1, M-2, M-3S-2

Kryterium oceny - wiedza

Efekt uczenia sięOcenaKryterium oceny
BTap_2A_BTA-S-O7.2_W01
Student has knowledge about the organization and structural relationships of proteins. He knows bioinformatic methods and tools for the analysis of protein structures. Has knowledge about the possibilities and consequences of manipulation in protein structures.
2,0
3,0Preparation of a multimedia presentation, participation in 90% of auditory classes, Correct answer to 60% of test questions - exam
3,5
4,0
4,5
5,0

Kryterium oceny - umiejętności

Efekt uczenia sięOcenaKryterium oceny
BTap_2A_BTA-S-O7.2_U01
Correctly applying a bioinformatic tools to 3D enzymes structure solving
2,0
3,0Preparation of a multimedia presentation, participation in 90% of auditory classes,
3,5
4,0
4,5
5,0

Kryterium oceny - inne kompetencje społeczne i personalne

Efekt uczenia sięOcenaKryterium oceny
BTap_2A_BTA-S-O7.2_K01
Understands the consequences of modifying protein structures on the functioning of living organisms
2,0
3,0Preparation of a multimedia presentation, participation in 90% of auditory classes,
3,5
4,0
4,5
5,0

Literatura podstawowa

  1. K. I. Ramachandran, Gopakumar Deepa, Krishnan Namboori, Computational Chemistry and Molecular Modeling: Principles and Applications, Springer, Berlin Heidelberg, 2008
  2. Paul G. Higgs, Teresa K. Attwood, Bioinformatics and Molecular Evolution, Wiley-Blackwell, USA, 2005, I
  3. Huzefa Rangwala, George Karypis (Ed.), Introduction to Protein Structure Prediction: Methods and Algorithms, Wiley, USA, 2011, I
  4. Andrzej Koliński red., Multiscale Approaches to Protein Modeling, Springer, 2010, I

Literatura dodatkowa

  1. Alan Cooper, Biophysical Chemistry, RSC, 2010, II

Treści programowe - laboratoria

KODTreść programowaGodziny
T-L-1The introduction to proteins molecular structure part I2
T-L-2The introduction to proteins molecular structure part II2
T-L-3The in silico methods of proteins structure II and III level determination4
T-L-4Methods of enzymes structure ligand binding site determination.2
T-L-5The methods for the effective ligands design for the enzymes activity modulation.5
15

Treści programowe - wykłady

KODTreść programowaGodziny
T-W-1Principles of proteins structure organisation part I. Methods for the data mining for protein structure on their I level.2
T-W-2Priciples of proteins structure organisation part II. Methods for the data mining for protein structure on their II and III level.2
T-W-3Computionial methods for prediction of localisation the enzymes acitive site.2
T-W-4Computational methods for enzymes catalytic sites properities determination.2
T-W-5Modeling of the catalytic properities of enzymes - pH and thermal optima,2
T-W-6Molecular docking as tool for design an enzymes inhibitors. Part I2
T-W-7Molecular docking as tool for design an enzymes inhibitors. Part II2
T-W-8Molecular modeling software for enzyme analysis and modelling1
15

Formy aktywności - laboratoria

KODForma aktywnościGodziny
A-L-1Participation in the classes.15
A-L-2Individual study of training materials8
A-L-3consultations2
25
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta

Formy aktywności - wykłady

KODForma aktywnościGodziny
A-W-1Participation in lectures.15
A-W-2Consultation2
A-W-3Preparation for passing the lecture content.8
25
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięBTap_2A_BTA-S-O7.2_W01Student has knowledge about the organization and structural relationships of proteins. He knows bioinformatic methods and tools for the analysis of protein structures. Has knowledge about the possibilities and consequences of manipulation in protein structures.
Odniesienie do efektów kształcenia dla kierunku studiówBTap_2A_W01has an extended knowledge in the field of biology, chemistry, mathematics, physics and related sciences adapted to the biotechnology field
Cel przedmiotuC-1Developing skills of selection of appropriate bioinformatics tools to solve and analyze the structure of proteins
C-2Mastering the ability to combine and correct interpretation of information relating to various levels of organization of protein structures
Treści programoweT-L-1The introduction to proteins molecular structure part I
T-L-3The in silico methods of proteins structure II and III level determination
T-L-5The methods for the effective ligands design for the enzymes activity modulation.
Metody nauczaniaM-1Information lectures
M-2Explanation or clarification
M-3Description
Sposób ocenyS-2Ocena formująca: multimedia presentation
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Preparation of a multimedia presentation, participation in 90% of auditory classes, Correct answer to 60% of test questions - exam
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięBTap_2A_BTA-S-O7.2_U01Correctly applying a bioinformatic tools to 3D enzymes structure solving
Odniesienie do efektów kształcenia dla kierunku studiówBTap_2A_U05can individually and in a group design and implement experimental process, including measurements, applicable in biotechnology; interprets the results obtained and draws conclusions; conducts discussions based on self-knowledge acquired using specialist language
Cel przedmiotuC-1Developing skills of selection of appropriate bioinformatics tools to solve and analyze the structure of proteins
C-2Mastering the ability to combine and correct interpretation of information relating to various levels of organization of protein structures
Treści programoweT-W-1Principles of proteins structure organisation part I. Methods for the data mining for protein structure on their I level.
T-W-2Priciples of proteins structure organisation part II. Methods for the data mining for protein structure on their II and III level.
T-W-3Computionial methods for prediction of localisation the enzymes acitive site.
T-W-4Computational methods for enzymes catalytic sites properities determination.
Metody nauczaniaM-3Description
Sposób ocenyS-2Ocena formująca: multimedia presentation
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Preparation of a multimedia presentation, participation in 90% of auditory classes,
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięBTap_2A_BTA-S-O7.2_K01Understands the consequences of modifying protein structures on the functioning of living organisms
Odniesienie do efektów kształcenia dla kierunku studiówBTap_2A_K02demonstrates understanding of biotechnological processes used in various areas of human activity; interprets and describes these processes using a scientific approach
Cel przedmiotuC-1Developing skills of selection of appropriate bioinformatics tools to solve and analyze the structure of proteins
C-2Mastering the ability to combine and correct interpretation of information relating to various levels of organization of protein structures
Treści programoweT-L-1The introduction to proteins molecular structure part I
T-L-3The in silico methods of proteins structure II and III level determination
T-L-5The methods for the effective ligands design for the enzymes activity modulation.
Metody nauczaniaM-1Information lectures
M-2Explanation or clarification
M-3Description
Sposób ocenyS-2Ocena formująca: multimedia presentation
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Preparation of a multimedia presentation, participation in 90% of auditory classes,
3,5
4,0
4,5
5,0