Zachodniopomorski Uniwersytet Technologiczny w Szczecinie

Wydział Technologii i Inżynierii Chemicznej - Chemical Engineering (S1)

Sylabus przedmiotu Introduction to Pharmaceutical Engineering:

Informacje podstawowe

Kierunek studiów Chemical Engineering
Forma studiów studia stacjonarne Poziom pierwszego stopnia
Tytuł zawodowy absolwenta inżynier
Obszary studiów charakterystyki PRK, kompetencje inżynierskie PRK
Profil ogólnoakademicki
Moduł —
Przedmiot Introduction to Pharmaceutical Engineering
Specjalność przedmiot wspólny
Jednostka prowadząca Katedra Inżynierii Polimerów i Biomateriałów
Nauczyciel odpowiedzialny Piotr Sobolewski <psobolewski@zut.edu.pl>
Inni nauczyciele Małgorzata Dzięcioł <Malgorzata.Dzieciol@zut.edu.pl>, Piotr Sobolewski <psobolewski@zut.edu.pl>
ECTS (planowane) 6,0 ECTS (formy) 6,0
Forma zaliczenia zaliczenie Język angielski
Blok obieralny 5 Grupa obieralna 2

Formy dydaktyczne

Forma dydaktycznaKODSemestrGodzinyECTSWagaZaliczenie
laboratoriaL5 45 4,00,50zaliczenie
wykładyW5 30 2,00,50zaliczenie

Wymagania wstępne

KODWymaganie wstępne
W-1Introduction to chemistry

Cele przedmiotu

KODCel modułu/przedmiotu
C-1Define important keywords and concepts
C-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation

Treści programowe z podziałem na formy zajęć

KODTreść programowaGodziny
laboratoria
T-L-1Synthesis, purification & analysis of selected active compound15
T-L-2Drug formulation10
T-L-3Quality control of pharmaceutical product5
T-L-4Nanocarriers for drug delivery7
T-L-5Dose response in vitro8
45
wykłady
T-W-1Introduction: history and definitions1
T-W-2Unit Processes12
T-W-3Unit Operations2
T-W-4Drug Formulations4
T-W-5Quality Control2
T-W-6Pharmacokinetics & Pharmacodynamics5
T-W-7Drug Delivery Systems4
30

Obciążenie pracą studenta - formy aktywności

KODForma aktywnościGodziny
laboratoria
A-L-1Participation in lab exercize45
A-L-2Preparing for lab (readings)30
A-L-3Preparing lab reports45
120
wykłady
A-W-1Participation in lecture30
A-W-2Preparing for class (readings)15
A-W-3Independent study15
60

Metody nauczania / narzędzia dydaktyczne

KODMetoda nauczania / narzędzie dydaktyczne
M-1Laboratory Exercises
M-2Powerpoint and whiteboard lectures
M-3In-class discussion

Sposoby oceny

KODSposób oceny
S-1Ocena formująca: Evaluation of working in the laboratory
S-2Ocena podsumowująca: Evaluation of written reports
S-3Ocena podsumowująca: Exam

Zamierzone efekty uczenia się - wiedza

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
ChEn_1A_C16b_W01
Student will be able to describe the biological activity of selected medicines		ChEn_1A_W13, ChEn_1A_W15——C-1, C-2, C-3, C-4T-W-1, T-W-2, T-W-3, T-W-4, T-W-5, T-W-6, T-W-7M-1S-2
ChEn_1A_C16b_W02
Student will be able to characterize the synthesis methods of selected medicines		ChEn_1A_W13, ChEn_1A_W15——C-2, C-3, C-4T-L-1, T-W-2, T-W-3, T-W-4, T-W-6M-1S-2

Zamierzone efekty uczenia się - umiejętności

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
ChEn_1A_C16b_U01
Student will be able to perform the synthesis and analysis of selected medicines following the instruction		ChEn_1A_U01, ChEn_1A_U03, ChEn_1A_U05, ChEn_1A_U08, ChEn_1A_U16——C-2, C-3, C-4T-L-1, T-L-2, T-L-3, T-L-4, T-L-5M-1S-1
ChEn_1A_C16b_U02
Student will be able to collect and organize data from literature.		ChEn_1A_U01, ChEn_1A_U03, ChEn_1A_U05, ChEn_1A_U08, ChEn_1A_U16——C-2, C-3, C-4T-L-1, T-L-2, T-L-3, T-L-4, T-L-5M-1S-2

Zamierzone efekty uczenia się - inne kompetencje społeczne i personalne

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
ChEn_1A_C16b_K01
Student will be aware of biological effects associated with the use of medicines		ChEn_1A_K01, ChEn_1A_K03, ChEn_1A_K04, ChEn_1A_K05——C-2, C-3, C-4T-W-2, T-W-3, T-W-4, T-W-5, T-W-6, T-W-7M-1S-2

Kryterium oceny - wiedza

Efekt uczenia sięOcenaKryterium oceny
ChEn_1A_C16b_W01
Student will be able to describe the biological activity of selected medicines		2,0
3,0Student is able to describe the basics of biological activity of selected medicines
3,5
4,0
4,5
5,0
ChEn_1A_C16b_W02
Student will be able to characterize the synthesis methods of selected medicines		2,0
3,0Student is able to describe the basic synthesis methods of selected medicines
3,5
4,0
4,5
5,0

Kryterium oceny - umiejętności

Efekt uczenia sięOcenaKryterium oceny
ChEn_1A_C16b_U01
Student will be able to perform the synthesis and analysis of selected medicines following the instruction		2,0
3,0Student is able to perform the synthesis and analysis of selected medicines following the instruction with help of the teacher
3,5
4,0
4,5
5,0
ChEn_1A_C16b_U02
Student will be able to collect and organize data from literature.		2,0
3,0student is able to prepare a report on a specified topic
3,5
4,0
4,5
5,0

Kryterium oceny - inne kompetencje społeczne i personalne

Efekt uczenia sięOcenaKryterium oceny
ChEn_1A_C16b_K01
Student will be aware of biological effects associated with the use of medicines		2,0
3,0Student is aware of biological effects associated with the use of medicines
3,5
4,0
4,5
5,0

Literatura podstawowa

  1. Lednicer D., The Organic Chemistry of Drug Synthesis, Wiley, New York, 1995
  2. Kleemann A., Engel J., Pharmaceutical Substances. Syntheses, Patents, Applications, Thieme, Stuttgard, 2001, 4th Ed.
  3. Gad S.C., Pharmaceutical Manufacturing Handbook. Production and Processes, John Wiley & Sons, Inc., New Jersey, 2008
  4. Furniss B.S., Hannaford A.J., Smith, P.W.G., Tatchell A.R., Vogel’s Textbook of Practical Organic chemistry, The School of Chemistry, Thames Polytechnic, London, 1989, 5th Ed.
  5. Joseph DiPiro, Introduction to Pharmacokinetics and Pharmacodynamics, ASHP, 2010, in: Concepts in Clinical Pharmacokinetics

Literatura dodatkowa

  1. Crist et al., Common pitfalls in nanotechnology: lessons learned from NCI’s Nanotechnology Characterization Laboratory, Integrative Biology, 2013, 5, 66, 10.1039/c2ib20117h
  2. Kim et al, Nanomedicine, NEJM, 2010, 363, 25, 2434, 10.1056/NEJMra0912273

Treści programowe - laboratoria

KODTreść programowaGodziny
T-L-1Synthesis, purification & analysis of selected active compound15
T-L-2Drug formulation10
T-L-3Quality control of pharmaceutical product5
T-L-4Nanocarriers for drug delivery7
T-L-5Dose response in vitro8
45

Treści programowe - wykłady

KODTreść programowaGodziny
T-W-1Introduction: history and definitions1
T-W-2Unit Processes12
T-W-3Unit Operations2
T-W-4Drug Formulations4
T-W-5Quality Control2
T-W-6Pharmacokinetics & Pharmacodynamics5
T-W-7Drug Delivery Systems4
30

Formy aktywności - laboratoria

KODForma aktywnościGodziny
A-L-1Participation in lab exercize45
A-L-2Preparing for lab (readings)30
A-L-3Preparing lab reports45
120
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta

Formy aktywności - wykłady

KODForma aktywnościGodziny
A-W-1Participation in lecture30
A-W-2Preparing for class (readings)15
A-W-3Independent study15
60
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C16b_W01Student will be able to describe the biological activity of selected medicines
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_W13Has knowledge of the current state and the latest developmental trends in chemical engineering and technology as well as the related areas in Poland and abroad.
ChEn_1A_W15Knows basic methods, techniques, tools and materials used for solving simple engineering tasks within the scope of chemical engineering and technology.
Cel przedmiotuC-1Define important keywords and concepts
C-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-W-1Introduction: history and definitions
T-W-2Unit Processes
T-W-3Unit Operations
T-W-4Drug Formulations
T-W-5Quality Control
T-W-6Pharmacokinetics & Pharmacodynamics
T-W-7Drug Delivery Systems
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is able to describe the basics of biological activity of selected medicines
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C16b_W02Student will be able to characterize the synthesis methods of selected medicines
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_W13Has knowledge of the current state and the latest developmental trends in chemical engineering and technology as well as the related areas in Poland and abroad.
ChEn_1A_W15Knows basic methods, techniques, tools and materials used for solving simple engineering tasks within the scope of chemical engineering and technology.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-L-1Synthesis, purification & analysis of selected active compound
T-W-2Unit Processes
T-W-3Unit Operations
T-W-4Drug Formulations
T-W-6Pharmacokinetics & Pharmacodynamics
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is able to describe the basic synthesis methods of selected medicines
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C16b_U01Student will be able to perform the synthesis and analysis of selected medicines following the instruction
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_U01Is able to obtain information from literature, data bases and other sources related to chemical engineering and technology as well as related areas; is able to integrate the obtained information, interpret it, draw proper conclusions and formulate opinions with their justification.
ChEn_1A_U03Is able to prepare, in English or another foreign language, a well-documented study of problems within the scope of chemical and process engineering; is able to develop documentation concerning the accomplishment of an engineering task.
ChEn_1A_U05Has the ability to learn, e.g. to raise professional competences.
ChEn_1A_U08Is able to plan and conduct process experiments, including measurements and computer simulations, as well as to interpret the obtained results and draw conclusions.
ChEn_1A_U16Is able to assess the usefulness of routine methods and tools used for solving a simple engineering task of practical nature characteristic for chemical engineering and technology as well as select and use a proper performance method and tools.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-L-1Synthesis, purification & analysis of selected active compound
T-L-2Drug formulation
T-L-3Quality control of pharmaceutical product
T-L-4Nanocarriers for drug delivery
T-L-5Dose response in vitro
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-1Ocena formująca: Evaluation of working in the laboratory
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is able to perform the synthesis and analysis of selected medicines following the instruction with help of the teacher
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C16b_U02Student will be able to collect and organize data from literature.
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_U01Is able to obtain information from literature, data bases and other sources related to chemical engineering and technology as well as related areas; is able to integrate the obtained information, interpret it, draw proper conclusions and formulate opinions with their justification.
ChEn_1A_U03Is able to prepare, in English or another foreign language, a well-documented study of problems within the scope of chemical and process engineering; is able to develop documentation concerning the accomplishment of an engineering task.
ChEn_1A_U05Has the ability to learn, e.g. to raise professional competences.
ChEn_1A_U08Is able to plan and conduct process experiments, including measurements and computer simulations, as well as to interpret the obtained results and draw conclusions.
ChEn_1A_U16Is able to assess the usefulness of routine methods and tools used for solving a simple engineering task of practical nature characteristic for chemical engineering and technology as well as select and use a proper performance method and tools.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-L-1Synthesis, purification & analysis of selected active compound
T-L-2Drug formulation
T-L-3Quality control of pharmaceutical product
T-L-4Nanocarriers for drug delivery
T-L-5Dose response in vitro
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0student is able to prepare a report on a specified topic
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C16b_K01Student will be aware of biological effects associated with the use of medicines
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_K01Understands the need of learning and raising professional and personal competences, motivating other colleagues.
ChEn_1A_K03Is able to cooperate and work in a group. Is able to perform the function of a team leader; is able to estimate the time necessary to accomplish the assigned task.
ChEn_1A_K04Is able to determine the priorities used for performance of the tasks of his/her own or other team members in order to achieve the goal set.
ChEn_1A_K05Is able to manage his/her own professional development, taking decisions and solving problems, including interpersonal ones connected with job performance.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-W-2Unit Processes
T-W-3Unit Operations
T-W-4Drug Formulations
T-W-5Quality Control
T-W-6Pharmacokinetics & Pharmacodynamics
T-W-7Drug Delivery Systems
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is aware of biological effects associated with the use of medicines
3,5
4,0
4,5
5,0