Wydział Technologii i Inżynierii Chemicznej - Chemical Engineering (S1)
Sylabus przedmiotu Introduction to Pharmaceutical Technology and Analysis:
Informacje podstawowe
| Kierunek studiów | Chemical Engineering | ||
|---|---|---|---|
| Forma studiów | studia stacjonarne | Poziom | pierwszego stopnia |
| Tytuł zawodowy absolwenta | inżynier | ||
| Obszary studiów | charakterystyki PRK, kompetencje inżynierskie PRK | ||
| Profil | ogólnoakademicki | ||
| Moduł | — | ||
| Przedmiot | Introduction to Pharmaceutical Technology and Analysis | ||
| Specjalność | przedmiot wspólny | ||
| Jednostka prowadząca | Katedra Technologii Chemicznej Organicznej i Materiałów Polimerowych | ||
| Nauczyciel odpowiedzialny | Małgorzata Dzięcioł <Malgorzata.Dzieciol@zut.edu.pl> | ||
| Inni nauczyciele | |||
| ECTS (planowane) | 6,0 | ECTS (formy) | 6,0 |
| Forma zaliczenia | egzamin | Język | angielski |
| Blok obieralny | 8 | Grupa obieralna | 2 |
Formy dydaktyczne
Wymagania wstępne
| KOD | Wymaganie wstępne |
|---|---|
| W-1 | Introduction to chemistry |
Cele przedmiotu
| KOD | Cel modułu/przedmiotu |
|---|---|
| C-1 | Define important definitions and key words |
| C-2 | Knowledge and skills related to the basic technologies and processes applied for obtaining, purification and characterization of pharmacologically active substances and formulations |
| C-3 | Understand the role and application of different analytical methods in quality control of pharmaceuticals |
| C-4 | Discuss delivery-related design considerations of a drug formulation |
Treści programowe z podziałem na formy zajęć
| KOD | Treść programowa | Godziny |
|---|---|---|
| laboratoria | ||
| T-L-1 | Selected methods of synthesis of active pharmaceutical ingredients (API) | 10 |
| T-L-2 | Identification, assessment of the purity and determination of physicochemical properties of obtained active pharmaceutical ingredients (API). Characteristic reactions of selected API groups | 5 |
| T-L-3 | Application of chromatographic and spectroscopic methods in quality control of pharmaceutical products | 10 |
| T-L-4 | Isolation and analysis of selected pharmacologically active substances from plants | 5 |
| T-L-5 | Microspheres for Drug Delivery: Preparation | 5 |
| T-L-6 | Microspheres for Drug Delievery: Characterization | 5 |
| T-L-7 | In vitro drug release study | 5 |
| 45 | ||
| wykłady | ||
| T-W-1 | History of drugs development, sources of drugs | 2 |
| T-W-2 | Technological processes for obtaining of selected active pharmaceutical ingredients (API) - theoretical and practical basics | 8 |
| T-W-3 | Types of excipients and their functions in drug formulations for different routes of administration | 4 |
| T-W-4 | Analytical methods applied in quality control of pharmaceuticals. Identification of active substances. Types of impurities in drugs and their sources. Falsified medicines | 6 |
| T-W-5 | Routes of Delivery, Pharmacokinetics & Pharmacodynamics | 4 |
| T-W-6 | Controlled Release | 4 |
| T-W-7 | Pharmaceutical Process development and GMP | 2 |
| 30 | ||
Obciążenie pracą studenta - formy aktywności
| KOD | Forma aktywności | Godziny |
|---|---|---|
| laboratoria | ||
| A-L-1 | Participation in laboratory classes | 45 |
| A-L-2 | Preparing for labs (readings) | 10 |
| A-L-3 | Preparing labs reports | 18 |
| A-L-4 | Consultations | 2 |
| 75 | ||
| wykłady | ||
| A-W-1 | Participation in lecture | 30 |
| A-W-2 | Exam | 3 |
| A-W-3 | Preparing for class (readings) | 10 |
| A-W-4 | Independent study | 10 |
| A-W-5 | Preparing for the exam | 20 |
| A-W-6 | Consultations | 2 |
| 75 | ||
Metody nauczania / narzędzia dydaktyczne
| KOD | Metoda nauczania / narzędzie dydaktyczne |
|---|---|
| M-1 | Laboratory classes |
| M-2 | Powerpoint and whiteboard lectures |
| M-3 | In-class discussion |
Sposoby oceny
| KOD | Sposób oceny |
|---|---|
| S-1 | Ocena formująca: Evaluation of working in the laboratory |
| S-2 | Ocena podsumowująca: Evaluation of written reports |
| S-3 | Ocena podsumowująca: Exam |
Zamierzone efekty uczenia się - wiedza
| Zamierzone efekty uczenia się | Odniesienie do efektów kształcenia dla kierunku studiów | Odniesienie do efektów zdefiniowanych dla obszaru kształcenia | Odniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżyniera | Cel przedmiotu | Treści programowe | Metody nauczania | Sposób oceny |
|---|---|---|---|---|---|---|---|
| ChEn_1A_C27b_W01 Student will be able to describe the biological activity of selected medicines | ChEn_1A_W13, ChEn_1A_W15 | — | — | C-1, C-2, C-3, C-4 | T-W-1, T-W-2, T-W-4, T-W-5, T-W-6, T-W-3, T-W-7 | M-1, M-2, M-3 | S-2, S-3 |
| ChEn_1A_C27b_W02 Student will be able to characterize fundamentals of pharmaceutical technological processes, including obtaining and purification of selected active pharmaceutical ingredients (API), drug formulation and delivery systems, analytical methods applied in quality control | ChEn_1A_W13, ChEn_1A_W15 | — | — | C-2, C-3, C-4, C-1 | T-W-2, T-W-5, T-W-6, T-W-1, T-W-7, T-W-3, T-W-4 | M-3, M-2, M-1 | S-3 |
Zamierzone efekty uczenia się - umiejętności
| Zamierzone efekty uczenia się | Odniesienie do efektów kształcenia dla kierunku studiów | Odniesienie do efektów zdefiniowanych dla obszaru kształcenia | Odniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżyniera | Cel przedmiotu | Treści programowe | Metody nauczania | Sposób oceny |
|---|---|---|---|---|---|---|---|
| ChEn_1A_C27b_U01 Student will be able to obtain selected pharmacologically active substances, prepare drug formulations and perform the analyses of pharmaceutical products following the instruction | ChEn_1A_U01, ChEn_1A_U03, ChEn_1A_U05, ChEn_1A_U08, ChEn_1A_U16 | — | — | C-2, C-3, C-4 | T-L-1, T-L-4, T-L-3, T-L-5, T-L-6, T-L-7, T-L-2 | M-1 | S-1, S-2 |
| ChEn_1A_C27b_U02 Student will be able to elaborate the experimental data and interpret the obtained results using data from literature | ChEn_1A_U01, ChEn_1A_U03, ChEn_1A_U05, ChEn_1A_U08, ChEn_1A_U16 | — | — | C-2, C-3, C-4 | T-L-1, T-L-4, T-L-3, T-L-5, T-L-6, T-L-2, T-L-7 | M-1 | S-2 |
Zamierzone efekty uczenia się - inne kompetencje społeczne i personalne
| Zamierzone efekty uczenia się | Odniesienie do efektów kształcenia dla kierunku studiów | Odniesienie do efektów zdefiniowanych dla obszaru kształcenia | Odniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżyniera | Cel przedmiotu | Treści programowe | Metody nauczania | Sposób oceny |
|---|---|---|---|---|---|---|---|
| ChEn_1A_C27b_K01 Student will be aware of the importance of quality control in pharmaceutical industry | ChEn_1A_K01, ChEn_1A_K05 | — | — | C-2, C-3, C-4 | T-W-2, T-W-4, T-W-5, T-W-6, T-L-5, T-L-2, T-W-3, T-W-7, T-L-1, T-L-6, T-L-4, T-L-3, T-L-7, T-W-1 | M-1, M-2, M-3 | S-2, S-1 |
Kryterium oceny - wiedza
| Efekt uczenia się | Ocena | Kryterium oceny |
|---|---|---|
| ChEn_1A_C27b_W01 Student will be able to describe the biological activity of selected medicines | 2,0 | |
| 3,0 | Student is able to describe the basics of biological activity of selected medicines | |
| 3,5 | ||
| 4,0 | ||
| 4,5 | ||
| 5,0 | ||
| ChEn_1A_C27b_W02 Student will be able to characterize fundamentals of pharmaceutical technological processes, including obtaining and purification of selected active pharmaceutical ingredients (API), drug formulation and delivery systems, analytical methods applied in quality control | 2,0 | |
| 3,0 | Student is able to describe the basics of selected technological processes and analytical methods applied in pharmaceutical industry | |
| 3,5 | ||
| 4,0 | ||
| 4,5 | ||
| 5,0 |
Kryterium oceny - umiejętności
| Efekt uczenia się | Ocena | Kryterium oceny |
|---|---|---|
| ChEn_1A_C27b_U01 Student will be able to obtain selected pharmacologically active substances, prepare drug formulations and perform the analyses of pharmaceutical products following the instruction | 2,0 | |
| 3,0 | Student is able to perform the synthesis, formulation and analysis of selected medicines following the instruction with help of the teacher | |
| 3,5 | ||
| 4,0 | ||
| 4,5 | ||
| 5,0 | ||
| ChEn_1A_C27b_U02 Student will be able to elaborate the experimental data and interpret the obtained results using data from literature | 2,0 | |
| 3,0 | Student is able to prepare a report from laboratory classes with basic required data | |
| 3,5 | ||
| 4,0 | ||
| 4,5 | ||
| 5,0 |
Kryterium oceny - inne kompetencje społeczne i personalne
| Efekt uczenia się | Ocena | Kryterium oceny |
|---|---|---|
| ChEn_1A_C27b_K01 Student will be aware of the importance of quality control in pharmaceutical industry | 2,0 | |
| 3,0 | Student is aware of importance of pharmaceuticals quality control | |
| 3,5 | ||
| 4,0 | ||
| 4,5 | ||
| 5,0 |
Literatura podstawowa
- Lednicer D., The Organic Chemistry of Drug Synthesis, Wiley, New York, 1995
- Kleemann A., Engel J., Pharmaceutical Substances. Syntheses, Patents, Applications, Thieme, Stuttgard, 2001, 4th Ed.
- Gad S.C., Pharmaceutical Manufacturing Handbook. Production and Processes, John Wiley & Sons, Inc., New Jersey, 2008
Literatura dodatkowa
- Crist et al., Common pitfalls in nanotechnology: lessons learned from NCI’s Nanotechnology Characterization Laboratory, Integrative Biology, 2013, 5, 66, 10.1039/c2ib20117h
- Kim et al, Nanomedicine, NEJM, 2010, 363, 25, 2434, 10.1056/NEJMra0912273
- Furniss B.S., Hannaford A.J., Smith, P.W.G., Tatchell A.R., Vogel’s Textbook of Practical Organic chemistry, The School of Chemistry, Thames Polytechnic, London, 1989, 5th Ed.
- Joseph DiPiro, Introduction to Pharmacokinetics and Pharmacodynamics, ASHP, 2010, in: Concepts in Clinical Pharmacokinetics