Zachodniopomorski Uniwersytet Technologiczny w Szczecinie

Wydział Biotechnologii i Hodowli Zwierząt - Biotechnologia (S2)

Sylabus przedmiotu Environmental toxicology:

Informacje podstawowe

Kierunek studiów Biotechnologia
Forma studiów studia stacjonarne Poziom drugiego stopnia
Tytuł zawodowy absolwenta magister inżynier
Obszary studiów nauki rolnicze, leśne i weterynaryjne, studia inżynierskie
Profil ogólnoakademicki
Moduł
Przedmiot Environmental toxicology
Specjalność Biotechnology in animal production and environmental protection
Jednostka prowadząca Katedra Biotechnologii Rozrodu Zwierząt i Higieny Środowiska
Nauczyciel odpowiedzialny Agnieszka Tomza-Marciniak <Agnieszka.Tomza-Marciniak@zut.edu.pl>
Inni nauczyciele Bogumiła Pilarczyk <Bogumila.Pilarczyk@zut.edu.pl>
ECTS (planowane) 3,0 ECTS (formy) 3,0
Forma zaliczenia egzamin Język polski
Blok obieralny Grupa obieralna

Formy dydaktyczne

Forma dydaktycznaKODSemestrGodzinyECTSWagaZaliczenie
wykładyW2 15 1,50,50zaliczenie
ćwiczenia audytoryjneA2 15 1,50,50zaliczenie

Wymagania wstępne

KODWymaganie wstępne
W-1Knowledge of issues related to ecology and environmental protection.

Cele przedmiotu

KODCel modułu/przedmiotu
C-1To acquaint students with the toxicological characteristic of selected environmental pollutants.
C-2To acquaint students with metabolism of toxins.
C-3To acquaint students with factors influencing toxicity of xenobiotics.
C-4To acquaint students with the basic mechanisms of functional disorders and morphological changes in selected organs and systems.

Treści programowe z podziałem na formy zajęć

KODTreść programowaGodziny
ćwiczenia audytoryjne
T-A-1Toxicity testing of xenobiotics. Degrees of toxicity. Dose-response relationship.4
T-A-2Bioconcetration, bioaccumulation and biomagnification. Determination of BCF, BSAF and BMF (for different types ecosystems).2
T-A-3Toxicological characteristics of metals (Cd, Hg, Pb, Cu, Cr) and metalloid (As, Si). Source of pollution, route of absorption, fate and mechanism of toxicity. MRLs.2
T-A-4Estimation of dietary daily intake of toxic elements.2
T-A-5Persistent organic pollutants (POPs) - toxicological characteristcs.2
T-A-6Estimation of dietary daily intake of selected POPs.3
15
wykłady
T-W-1Pollution and their fate in aquatic and terrestrial ecosystems. Classes of contaminants. Global transport of pollution. Factors determining the distribution of pollutants in the environment. Models of pollutants spread in the environment.2
T-W-2Metabolism of xenobiotics.2
T-W-3Factors affecting the toxicity of xenobiotics (the physicochemical properties - dissociation, solubility, particle size, biological factors - age, sex, individual development). Genetic factors versus accumulation and biotransformation of xenobiotics.2
T-W-4The biochemical effects of impurities (induction of detoxifying enzymes, and proteins capable of binding to heavy metal inhibition of cholinesterase, endocrine dysfunction, DNA adduct formation). Physiological effects of pollution (osmoregulation disorders, metabolic and neurological). The effects of toxicological interactions (additive effects, toxicity potentiation, antagonism).2
T-W-5Mutagenic and carcinogenic effects of xenobiotics. The impact of environmental pollution on the development of cancer. Types of carcinogens (genotoxic - working directly influence the metabolic activation; epigenetic - promoters, cytotoxic compounds, modifiers of hormones, immunosuppressive compounds).2
T-W-6Poisons of animal origin (poisons of insects, snakes, scorpions, fish). Symptoms and mechanism of toxicity.2
T-W-7Toxicological characteristics of plastics. Toxicological classification of some preparations used in households.3
15

Obciążenie pracą studenta - formy aktywności

KODForma aktywnościGodziny
ćwiczenia audytoryjne
A-A-1participation in lectures15
A-A-2preparation for test15
A-A-3studying indicated literature15
45
wykłady
A-W-1participation in lectures15
A-W-2preparation for test15
A-W-3studying indicated literature15
45

Metody nauczania / narzędzia dydaktyczne

KODMetoda nauczania / narzędzie dydaktyczne
M-1Delivery method, lecture/presentation
M-2Discussion
M-3Explanation

Sposoby oceny

KODSposób oceny
S-1Ocena podsumowująca: test
S-2Ocena formująca: continuous assessment

Zamierzone efekty kształcenia - wiedza

Zamierzone efekty kształceniaOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów kształcenia prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
BT_2A_BTZ-A-C2_W01
The student discusses the toxins biotransformation and factors affecting the toxicity of xenobiotics.
BT_2A_W06, BT_2A_W12C-2T-W-2, T-W-3M-1, M-3S-1
BT_2A_BTZ-A-C2_W02
Student discusses the mechanisms of functional disorders and changes morphological organs and systems under of selected toxins.
BT_2A_W01C-1, C-4T-W-4, T-W-5, T-W-6M-1, M-2, M-3S-1
BT_2A_BTZ-A-C2_W03
Student characterizes of selected xenobiotics.
BT_2A_W01, BT_2A_W12C-1T-W-1, T-W-7, T-A-3, T-A-4, T-A-2, T-A-5, T-A-6M-1, M-2, M-3S-1

Zamierzone efekty kształcenia - umiejętności

Zamierzone efekty kształceniaOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów kształcenia prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
BT_2A_BTZ-A-C2_U01
Student is able to calculate the LD50 for a specific subtance with using different methods.
BT_2A_U05C-1T-A-1M-3S-2

Zamierzone efekty kształcenia - inne kompetencje społeczne i personalne

Zamierzone efekty kształceniaOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów kształcenia prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
BT_2A_BTZ-A-C2_K01
The student demonstrates an active engagement with solving the identified problems.
BT_2A_K05C-1, C-2, C-3T-W-2, T-W-1, T-W-4, T-W-7, T-W-5, T-W-3, T-W-6, T-A-1, T-A-3, T-A-4, T-A-2, T-A-5, T-A-6M-2S-2

Kryterium oceny - wiedza

Efekt kształceniaOcenaKryterium oceny
BT_2A_BTZ-A-C2_W01
The student discusses the toxins biotransformation and factors affecting the toxicity of xenobiotics.
2,0
3,0The student describes the fate of toxins in the organism and explains the variability of the toxicity of specified substances.
3,5
4,0
4,5
5,0
BT_2A_BTZ-A-C2_W02
Student discusses the mechanisms of functional disorders and changes morphological organs and systems under of selected toxins.
2,0
3,0Student describes the mechanisms of functional disorders and morphological changes in the organs and systems by the action of selected toxins.
3,5
4,0
4,5
5,0
BT_2A_BTZ-A-C2_W03
Student characterizes of selected xenobiotics.
2,0
3,0Student correctly characterizes most of indicated xenobiotics.
3,5
4,0
4,5
5,0

Kryterium oceny - umiejętności

Efekt kształceniaOcenaKryterium oceny
BT_2A_BTZ-A-C2_U01
Student is able to calculate the LD50 for a specific subtance with using different methods.
2,0
3,0Student is able to calculate the LD50 for a indicated xenobiotic, using as at least 2 methods.
3,5
4,0
4,5
5,0

Kryterium oceny - inne kompetencje społeczne i personalne

Efekt kształceniaOcenaKryterium oceny
BT_2A_BTZ-A-C2_K01
The student demonstrates an active engagement with solving the identified problems.
2,0
3,0The student demonstrates an engagement with solving the identified problems but does not engage spontaneously.
3,5
4,0
4,5
5,0

Literatura podstawowa

  1. (Eds), General, Applied and Systems Toxicology, John Wiley and Sons, Online ISBN: 9780470744307, 2009, DOI: 10.1002/9780470744307

Treści programowe - ćwiczenia audytoryjne

KODTreść programowaGodziny
T-A-1Toxicity testing of xenobiotics. Degrees of toxicity. Dose-response relationship.4
T-A-2Bioconcetration, bioaccumulation and biomagnification. Determination of BCF, BSAF and BMF (for different types ecosystems).2
T-A-3Toxicological characteristics of metals (Cd, Hg, Pb, Cu, Cr) and metalloid (As, Si). Source of pollution, route of absorption, fate and mechanism of toxicity. MRLs.2
T-A-4Estimation of dietary daily intake of toxic elements.2
T-A-5Persistent organic pollutants (POPs) - toxicological characteristcs.2
T-A-6Estimation of dietary daily intake of selected POPs.3
15

Treści programowe - wykłady

KODTreść programowaGodziny
T-W-1Pollution and their fate in aquatic and terrestrial ecosystems. Classes of contaminants. Global transport of pollution. Factors determining the distribution of pollutants in the environment. Models of pollutants spread in the environment.2
T-W-2Metabolism of xenobiotics.2
T-W-3Factors affecting the toxicity of xenobiotics (the physicochemical properties - dissociation, solubility, particle size, biological factors - age, sex, individual development). Genetic factors versus accumulation and biotransformation of xenobiotics.2
T-W-4The biochemical effects of impurities (induction of detoxifying enzymes, and proteins capable of binding to heavy metal inhibition of cholinesterase, endocrine dysfunction, DNA adduct formation). Physiological effects of pollution (osmoregulation disorders, metabolic and neurological). The effects of toxicological interactions (additive effects, toxicity potentiation, antagonism).2
T-W-5Mutagenic and carcinogenic effects of xenobiotics. The impact of environmental pollution on the development of cancer. Types of carcinogens (genotoxic - working directly influence the metabolic activation; epigenetic - promoters, cytotoxic compounds, modifiers of hormones, immunosuppressive compounds).2
T-W-6Poisons of animal origin (poisons of insects, snakes, scorpions, fish). Symptoms and mechanism of toxicity.2
T-W-7Toxicological characteristics of plastics. Toxicological classification of some preparations used in households.3
15

Formy aktywności - ćwiczenia audytoryjne

KODForma aktywnościGodziny
A-A-1participation in lectures15
A-A-2preparation for test15
A-A-3studying indicated literature15
45
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta

Formy aktywności - wykłady

KODForma aktywnościGodziny
A-W-1participation in lectures15
A-W-2preparation for test15
A-W-3studying indicated literature15
45
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta
PoleKODZnaczenie kodu
Zamierzone efekty kształceniaBT_2A_BTZ-A-C2_W01The student discusses the toxins biotransformation and factors affecting the toxicity of xenobiotics.
Odniesienie do efektów kształcenia dla kierunku studiówBT_2A_W06ma szczegółową i uporządkowaną wiedzę z zakresu wykorzystania procesów molekularnych, enzymatycznych i fizjologicznych organizmów żywych w biotechnologii
BT_2A_W12wykazuje się zaawansowana znajomością z zakresu ochrony przyrody oraz potrafi samodzielnie definiować znaczenie środowiska, jego użytkowanie oraz zagrożenia z tym związane
Cel przedmiotuC-2To acquaint students with metabolism of toxins.
Treści programoweT-W-2Metabolism of xenobiotics.
T-W-3Factors affecting the toxicity of xenobiotics (the physicochemical properties - dissociation, solubility, particle size, biological factors - age, sex, individual development). Genetic factors versus accumulation and biotransformation of xenobiotics.
Metody nauczaniaM-1Delivery method, lecture/presentation
M-3Explanation
Sposób ocenyS-1Ocena podsumowująca: test
Kryteria ocenyOcenaKryterium oceny
2,0
3,0The student describes the fate of toxins in the organism and explains the variability of the toxicity of specified substances.
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty kształceniaBT_2A_BTZ-A-C2_W02Student discusses the mechanisms of functional disorders and changes morphological organs and systems under of selected toxins.
Odniesienie do efektów kształcenia dla kierunku studiówBT_2A_W01ma poszerzoną wiedzę z zakresu biologii, chemii, matematyki, fizyki oraz nauk pokrewnych dostosowaną do kierunku biotechnologia
Cel przedmiotuC-1To acquaint students with the toxicological characteristic of selected environmental pollutants.
C-4To acquaint students with the basic mechanisms of functional disorders and morphological changes in selected organs and systems.
Treści programoweT-W-4The biochemical effects of impurities (induction of detoxifying enzymes, and proteins capable of binding to heavy metal inhibition of cholinesterase, endocrine dysfunction, DNA adduct formation). Physiological effects of pollution (osmoregulation disorders, metabolic and neurological). The effects of toxicological interactions (additive effects, toxicity potentiation, antagonism).
T-W-5Mutagenic and carcinogenic effects of xenobiotics. The impact of environmental pollution on the development of cancer. Types of carcinogens (genotoxic - working directly influence the metabolic activation; epigenetic - promoters, cytotoxic compounds, modifiers of hormones, immunosuppressive compounds).
T-W-6Poisons of animal origin (poisons of insects, snakes, scorpions, fish). Symptoms and mechanism of toxicity.
Metody nauczaniaM-1Delivery method, lecture/presentation
M-2Discussion
M-3Explanation
Sposób ocenyS-1Ocena podsumowująca: test
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student describes the mechanisms of functional disorders and morphological changes in the organs and systems by the action of selected toxins.
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty kształceniaBT_2A_BTZ-A-C2_W03Student characterizes of selected xenobiotics.
Odniesienie do efektów kształcenia dla kierunku studiówBT_2A_W01ma poszerzoną wiedzę z zakresu biologii, chemii, matematyki, fizyki oraz nauk pokrewnych dostosowaną do kierunku biotechnologia
BT_2A_W12wykazuje się zaawansowana znajomością z zakresu ochrony przyrody oraz potrafi samodzielnie definiować znaczenie środowiska, jego użytkowanie oraz zagrożenia z tym związane
Cel przedmiotuC-1To acquaint students with the toxicological characteristic of selected environmental pollutants.
Treści programoweT-W-1Pollution and their fate in aquatic and terrestrial ecosystems. Classes of contaminants. Global transport of pollution. Factors determining the distribution of pollutants in the environment. Models of pollutants spread in the environment.
T-W-7Toxicological characteristics of plastics. Toxicological classification of some preparations used in households.
T-A-3Toxicological characteristics of metals (Cd, Hg, Pb, Cu, Cr) and metalloid (As, Si). Source of pollution, route of absorption, fate and mechanism of toxicity. MRLs.
T-A-4Estimation of dietary daily intake of toxic elements.
T-A-2Bioconcetration, bioaccumulation and biomagnification. Determination of BCF, BSAF and BMF (for different types ecosystems).
T-A-5Persistent organic pollutants (POPs) - toxicological characteristcs.
T-A-6Estimation of dietary daily intake of selected POPs.
Metody nauczaniaM-1Delivery method, lecture/presentation
M-2Discussion
M-3Explanation
Sposób ocenyS-1Ocena podsumowująca: test
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student correctly characterizes most of indicated xenobiotics.
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty kształceniaBT_2A_BTZ-A-C2_U01Student is able to calculate the LD50 for a specific subtance with using different methods.
Odniesienie do efektów kształcenia dla kierunku studiówBT_2A_U05Potrafi zaprojektować oraz zrealizować proces eksperymentalny; zna i stosuje metody oraz systemy diagnostyki laboratoryjnej i molekularnej; posiada umiejętność prowadzenia prac badawczych z użyciem materiału biologicznego; potrafi przeprowadzać badania z użyciem mikroskopów; stosuje w analizie i diagnostyce narzędzia bioinformatyczne. Zna systemy i procesy wykorzystywane w ocenie stanu środowiska.
Cel przedmiotuC-1To acquaint students with the toxicological characteristic of selected environmental pollutants.
Treści programoweT-A-1Toxicity testing of xenobiotics. Degrees of toxicity. Dose-response relationship.
Metody nauczaniaM-3Explanation
Sposób ocenyS-2Ocena formująca: continuous assessment
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is able to calculate the LD50 for a indicated xenobiotic, using as at least 2 methods.
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty kształceniaBT_2A_BTZ-A-C2_K01The student demonstrates an active engagement with solving the identified problems.
Odniesienie do efektów kształcenia dla kierunku studiówBT_2A_K05wykazuje zdyscyplinowanie w pracy indywidualnej; chętnie uczestniczy w pracy grupowej; potrafi kreatywnie planować i realizować działania własne i zespołowe
Cel przedmiotuC-1To acquaint students with the toxicological characteristic of selected environmental pollutants.
C-2To acquaint students with metabolism of toxins.
C-3To acquaint students with factors influencing toxicity of xenobiotics.
Treści programoweT-W-2Metabolism of xenobiotics.
T-W-1Pollution and their fate in aquatic and terrestrial ecosystems. Classes of contaminants. Global transport of pollution. Factors determining the distribution of pollutants in the environment. Models of pollutants spread in the environment.
T-W-4The biochemical effects of impurities (induction of detoxifying enzymes, and proteins capable of binding to heavy metal inhibition of cholinesterase, endocrine dysfunction, DNA adduct formation). Physiological effects of pollution (osmoregulation disorders, metabolic and neurological). The effects of toxicological interactions (additive effects, toxicity potentiation, antagonism).
T-W-7Toxicological characteristics of plastics. Toxicological classification of some preparations used in households.
T-W-5Mutagenic and carcinogenic effects of xenobiotics. The impact of environmental pollution on the development of cancer. Types of carcinogens (genotoxic - working directly influence the metabolic activation; epigenetic - promoters, cytotoxic compounds, modifiers of hormones, immunosuppressive compounds).
T-W-3Factors affecting the toxicity of xenobiotics (the physicochemical properties - dissociation, solubility, particle size, biological factors - age, sex, individual development). Genetic factors versus accumulation and biotransformation of xenobiotics.
T-W-6Poisons of animal origin (poisons of insects, snakes, scorpions, fish). Symptoms and mechanism of toxicity.
T-A-1Toxicity testing of xenobiotics. Degrees of toxicity. Dose-response relationship.
T-A-3Toxicological characteristics of metals (Cd, Hg, Pb, Cu, Cr) and metalloid (As, Si). Source of pollution, route of absorption, fate and mechanism of toxicity. MRLs.
T-A-4Estimation of dietary daily intake of toxic elements.
T-A-2Bioconcetration, bioaccumulation and biomagnification. Determination of BCF, BSAF and BMF (for different types ecosystems).
T-A-5Persistent organic pollutants (POPs) - toxicological characteristcs.
T-A-6Estimation of dietary daily intake of selected POPs.
Metody nauczaniaM-2Discussion
Sposób ocenyS-2Ocena formująca: continuous assessment
Kryteria ocenyOcenaKryterium oceny
2,0
3,0The student demonstrates an engagement with solving the identified problems but does not engage spontaneously.
3,5
4,0
4,5
5,0